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gene 2,143 words KG: GIGYF2
Contents

GIGYF2 — GRB10 Interacting GYF Protein 2

🧬 Gene Info
Gene SymbolGIGYF2
Full NameGRB10 Interacting GYF Protein 2
AliasesGRB10-Interacting GYF Protein 2
Chromosome5q33.21.
Protein FamilyGYF domain family, adaptor proteins
Protein TypeAdaptor Protein
Molecular Weight270 kDa
Amino Acids443 aa
PathwaysPI3K, MAPK, signaling: | Function | Mechanism |
UniProt IDQ9UHQ2
NCBI Gene ID26060
GeneCardsGIGYF2
Human Protein AtlasGIGYF2
Associated Diseasesneurodegeneration
KG Connections3 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

APOE-Dependent Autophagy Restoration
Score: 0.88FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (5)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedProtein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (3 edges)

GIGYF2 modulates Endothelial Cell Senescence
GBA intron-retained transcript recruits GIGYF2
GIGYF2 activates ribosome collision

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