gene 1,769 words KG: GFRA4
Contents

GFRA4 - GDNF Family Receptor Alpha 4

🧬 Gene Info
Gene SymbolGFRA4
Full NameGDNF Family Receptor Alpha 4
AliasesPage for GFRA4
Chromosome20p13
Protein TypeReceptor
Functionis a GPI-anchored cell surface receptor that serves as the primary receptor for persephin (PSPN).
Molecular Weight37 kDa
PathwaysPI3K, MAPK
UniProt IDQ9H3R5
NCBI Gene ID391720
GeneCardsGFRA4
Human Protein AtlasGFRA4
N-terminal signal peptideDirects GPI anchor attachment
Cysteine-rich domain (CRD)Stabilizes ligand-receptor complex
GPI anchor signal sequenceC-terminal signal for membrane attachment
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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