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gene 2,539 words KG: GEMIN5
Contents

GEMIN5 Gene

🧬 Gene Info
Gene SymbolGEMIN5
Chromosome14q12
Functionis a critical component of the SMN complex, the master regulator of spliceosomal snRNP (small nuclear ribonucleoprotein) assembly.
Molecular Weight175 kDa
Amino Acids1588 aa
Ensembl IDENSG00000140988
GeneCardsGEMIN5
Human Protein AtlasGEMIN5
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (9)

Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55Phase-Separated Organelle Targeting
Score: 0.73Stress Granule Phase Separation Modulators
Score: 0.72RNA Granule Nucleation Site Modulation
Score: 0.66Axonal RNA Transport Reconstitution
Score: 0.70Cross-Seeding Prevention Strategy
Score: 0.69Nucleolar Stress Response Normalization
Score: 0.65Glycine-Rich Domain Competitive Inhibition
Score: 0.64Cryptic Exon Silencing Restoration
Score: 0.53

Related Analyses (5)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedMicroglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archivedProtein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40Microglial Aging and Immune Memory in Neurodegeneration — Tr
validation · proposed · Score: 0.40Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40Synaptic Mitochondrial Resilience Enhancement for Parkinson'
validation · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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