| Gene Symbol | FER2 |
| Function | encodes a mitochondrial protein belonging to the ferredoxin family of iron-sulfur (Fe-S) proteins. |
| Primary Expression | steroidogenic tissues - FDX2 (Ferredoxin 2): Mitochondrial ferredoxin with overlapping functions - FDX1L (Ferredoxin 1-like): A truncated vari |
| Subcellular Localization | to mitochondria where it plays a critical role in [iro |
| Amino Acids | 120 aa |
| Ensembl ID | ENSG00000140497 |
| GeneCards | FER2 |
| Human Protein Atlas | FER2 |
| Conserved 2Fe-2S cluster binding domain | The signature region containing four conserved cysteine residues (Cys-X4-Cys-X2-Cys-X5-Cys motif) that ligate the iron-sulfur cluster |
| C-terminal acidic domain | A regionrich in acidic residues involved in protein-protein interactions |
| FDX1 (Ferredoxin 1) | Predominantly expressed in steroidogenic tissues |
| FDX2 (Ferredoxin 2) | Mitochondrial ferredoxin with overlapping functions |
| FDX1L (Ferredoxin 1-like) | A truncated variant |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!