| Gene Symbol | EEF1G |
| Full Name | Eukaryotic Translation Elongation Factor 1 Gamma |
| Chromosome | 11q12.3 |
| Function | is a critical subunit of the eukaryotic translation elongation factor 1 (EF-1) complex, which is essential for protein synthesis in all eukaryotic cells. |
| Primary Expression | various cancers, highlighting its importance in cell proliferation and survival[@edmunds2002] |
| Amino Acids | 437 aa |
| Ensembl ID | ENSG00000185208 |
| GeneCards | EEF1G |
| Human Protein Atlas | EEF1G |
| Cytoskeletal interactions | Associates with microtubules and actin filaments |
| Signal transduction | Involved in cellular signaling pathways |
| Dysregulated expression | Altered EEF1G levels in motor neurons of ALS patients |
| Stress granule formation | Participates in stress granule dynamics, which are disrupted in ALS |
| Protein homeostasis | Essential for maintaining proper translation under cellular stress |
| TDP-43 pathology | Interaction with TDP-43 protein aggregates |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!