| Gene Symbol | DnaJ Heat Shock Protein Family Member C26 |
| Aliases | DNAJC26 |
| Chromosome | 4p16.3 |
| Protein Type | Chaperone |
| Function | Key functions include |
| Pathways | TGF-β Signaling |
| UniProt ID | Q9UQF2 |
| NCBI Gene ID | 9907 |
| OMIM | 604393 |
| mRNA Binding and Regulation | G3BP2 binds to specific mRNA sequences and regulates translation during stress[@matsumoto2015] |
| Stress Granule Assembly | Acts as a scaffold protein, nucleating stress granule formation through interactions with multiple SG components |
| Translation Repression | Participates in mechanisms that stall translation under stress conditions |
| mRNA Decay | Associates with machinery involved in mRNA degradation pathways |
| TDP-43 | Sequestration of TDP-43 in stress granules is a hallmark of ALS/FTD[@nonaka2023] |
| FUS | Another ALS/FTD-associated protein that localizes to stress granules |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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