| Gene Symbol | DNAJC25 |
| Protein Type | Chaperone |
| Function | is a member of the DnaJ/Hsp40 family of co-chaperones that participate in cellular protein quality control mechanisms. |
| Primary Expression | various brain regions including the cortex, hippocampus, and cerebellum |
| Molecular Weight | 34 kDa |
| Amino Acids | 312 aa |
| GeneCards | DNAJC25 |
| Human Protein Atlas | DNAJC25 |
| Glycine-rich region | A flexible linker region containing glycine residues that may facilitate protein-protein interactions and provide flexibility between functional domains. |
| C-terminal substrate-binding domain | Region predicted to be involved in recognizing and binding client proteins, particularly those that are misfolded or partially unfolded. |
| Brain | Expressed in various brain regions including the cortex, hippocampus, and cerebellum. Expression has been detected in both neurons and supporting glial cells. |
| Peripheral tissues | Detected in liver, kidney, heart, and skeletal muscle at moderate levels. |
| Cellular compartments | Cytosolic localization with potential association with cellular membrane systems involved in protein quality control. |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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