| Gene Symbol | DAGLB |
| Full Name | Diacylglycerol Lipase Beta |
| Chromosome | 7q31.1 |
| Protein Type | Enzyme |
| Function | is a membrane-bound enzyme that catalyzes the hydrolysis of diacylglycerol to produce 2-AG[@stella1997]. |
| Primary Expression | brain regions involved in learning, memory, and motor control, including the hippocampus, [cortex](/brain-regions/cortex |
| Amino Acids | 672 aa |
| UniProt ID | Q8WWS3 |
| NCBI Gene ID | 27143 |
| Ensembl ID | ENSG00000153048 |
| GeneCards | DAGLB |
| Human Protein Atlas | DAGLB |
| Substrate specificity | Prefers sn-1,2-diacylglycerols with arachidonoyl (20:4) fatty acid chains |
| Regional distribution | Highest activity in the cerebellum, hippocampus, and prefrontal cortex |
| Cellular localization | Enriched in postsynaptic dendritic spines |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsHPASTRING |
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