| Gene Symbol | CPLX1 |
| Full Name | Complexin-1 |
| Function | Complexin-1 is a key regulator of synaptic transmission. |
| Primary Expression | the central nervous system, with high expression in the hippocampus, cerebral cortex, and cereb |
| Ensembl ID | ENSG00000130147 |
| GeneCards | CPLX1 |
| Human Protein Atlas | CPLX1 |
| Promote SNARE complex assembly | Complexin-1 stabilizes partially assembled SNARE complexes in a "fusion-competent" state |
| Trigger synchronous release | Upon Ca²⁺ influx through voltage-gated calcium channels, complexin-1 facilitates rapid vesicle fusion |
| Regulate spontaneous release | Modulates the rate of neurotransmitter release independent of action potentials |
| Prevent asynchronous release | Helps ensure precise timing of synaptic transmission |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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