| Gene Symbol | CLN2 |
| Full Name | Ceroid Lipofuscinosis 2 (TPP1) |
| Chromosome | 11p15.4 |
| Protein Type | Receptor |
| Function | It plays critical roles in ciliary signaling, neuronal migration, and synaptic function. |
| Primary Expression | regions affected in Parkinson disease |
| UniProt ID | O14773 |
| NCBI Gene ID | 1200 |
| Ensembl ID | ENSG00000100418 |
| OMIM | 607998 |
| GeneCards | CLN2 |
| Human Protein Atlas | CLN2 |
| AHI1 | Expressed in fetal and adult brain, with highest expression in cerebellum, basal ganglia, and hippocampus. Also expressed in kidney and testis. 6 |
| GAD1 | Broad expression in GABAergic neurons throughout the brain, including cortex, hippocampus, basal ganglia, and cerebellum. More abundant than GAD2 in most brain regions. 7 |
| GAD2 | Expressed in GABAergic neurons with synaptic localization. Higher expression in hippocampus and cerebellum compared to GAD1 in some regions. 8 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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