gene 2,028 words KG: CHASER
Contents

CYP11A1 Gene - Cholesterol Side-Chain Cleavage Enzyme

🧬 Gene Info
Gene SymbolCYP11A1
Full NameCytochrome P450 Family 11 Subfamily A Member 1
AliasesPage for CYP11A1 Gene (CHASER)
Chromosome15q24.2
Protein FamilyCytochrome P450
Protein TypeEnzyme
Functionis a critical enzyme in steroid biosynthesis and neurosteroid production.
Primary Expressionneurons and glial cells, where it contributes to local neurosteroid synthesis
Molecular Weight56 kDa
UniProt IDP05093
NCBI Gene ID1583
Ensembl IDENSG00000140359
OMIM118485
GeneCardsCYP11A1
Human Protein AtlasCYP11A1
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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Related Hypotheses (11)

Cholesterol-CRISPR Convergence Therapy for Neurodegeneration
Score: 0.62
CYP46A1 Overexpression Gene Therapy
Score: 0.95
Circadian Clock-Autophagy Synchronization
Score: 0.76
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Membrane Cholesterol Gradient Modulators
Score: 0.71
Lysosomal Enzyme Trafficking Correction
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Temporal Decoupling via Circadian Clock Reset
Score: 0.54
Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38

Related Analyses (5)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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