gene 1,299 words KG: CDC42EP1
Contents

CDC42EP1 Gene

🧬 Gene Info
Gene SymbolCDC42EP1
Full NameCDC42 Effector Protein 1
Chromosome16p13.3
FunctionCDC42 Binding: Active CDC42-GTP binds to the CRIB motif
Primary Expressionneurons where it plays critical roles in synaptic plasticity, dendritic spine morphology, and neuronal migration
Molecular Weight32 kDa
Amino Acids300 aa
Exons8
UniProt ID[Q9Y3E5](https://www.uniprot.org/uniprot/Q9Y3E5)
Ensembl IDENSG00000106628
GeneCardsCDC42EP1
Human Protein AtlasCDC42EP1
N-terminal CDC42-binding domain (CBD)Residues 1-80, mediates CDC42 interaction
Central regulatory regionContains phosphorylation sites
C-terminal effector domainRecruits downstream signaling molecules
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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