gene 1,296 words KG: CD3G
Contents

CD3G Gene

🧬 Gene Info
Gene SymbolCD3G
Full NameCD3 Gamma Subunit
Chromosome11q23.3
Protein TypeReceptor
FunctionWithout CD3γ, TCR complexes fail to reach the cell surface, leading to severe T-cell immunodeficiency[@clements1994].
Primary ExpressionT lymphocytes, where it plays a fundamental role in translating antigen recognition into intracellular signaling events that drive T-cell responses
UniProt IDP09693
NCBI Gene ID915
Ensembl IDENSG00000160654
OMIM186740
GeneCardsCD3G
Human Protein AtlasCD3G
Promoter regionContains elements for T-cell-specific expression
Exon regionsEncode the extracellular, transmembrane, and cytoplasmic domains
Regulatory elementsInclude enhancers and silencers for proper expression in T-cells
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsHPASTRING

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