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gene 783 words KG: CD300A
Contents

CD300A Gene

🧬 Gene Info
Gene SymbolCD300A
Chromosome17q25.1.
Protein TypeGene
Functionencodes an inhibitory immunoreceptor (CD300a, IRp60) expressed mainly in myeloid and lymphoid compartments, including microglia.
Molecular Weight33 kDa
Amino Acids296 aa
GeneCardsCD300A
Human Protein AtlasCD300A
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (8)

CYP46A1 Overexpression Gene Therapy
Score: 0.92Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76APOE-TREM2 Interaction Modulation
Score: 0.74Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69TREM2-mediated microglial tau clearance enhancement
Score: 0.62TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58TREM2-Dependent Microglial Senescence Transition
Score: 0.54

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedSynaptic pruning by microglia in early AD
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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