| Gene Symbol | CASP12 |
| Full Name | Cysteine-Containing Aspartate-Specific Protease 12 |
| Chromosome | 11q22.2 |
| Function | is a typical inactive zymogen consisting of |
| Primary Expression | Primarily in brain, muscle, and peripheral tissues |
| Amino Acids | 341 aa |
| UniProt ID | Q9Y252 |
| NCBI Gene ID | 100506658 |
| Ensembl ID | ENSG00000244045 |
| OMIM | 602394 |
| GeneCards | CASP12 |
| Human Protein Atlas | CASP12 |
| Exon 1 | Encodes the prodomain with the caspase recruitment domain (CARD) |
| Exons 2-6 | Encode the catalytic domains (p20 and p10 subunits) |
| African populations | ~60-80% express functional caspase-12 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease, ALS |
| Databases | GeneCardsHPASTRING |
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