gene 2,523 words KG: CA8
Contents

CA8 Gene - Carbonic Anhydrase VIII

🧬 Gene Info
Gene SymbolCA8
Full NameCarbonic Anhydrase VIII
Chromosome9
Functionencodes a member of the alpha-carbonic anhydrase family of zinc metalloenzymes.
Subcellular LocalizationCA8 is primarily localized in the cytoplasm, with some association with the plasma membrane. Importantly, CA8 shows part
Amino Acids290 aa
Exons7
Ensembl IDENSG00000168259
GeneCardsCA8
Human Protein AtlasCA8
Zinc-binding siteSubstituted with alanine and glycine residues
Proton shuttleReplaced by hydrophobic amino acids
Surface loopsModified to create protein-protein interaction interfaces
CerebellumHighest expression in Purkinje cells
Cerebral cortexModerate expression in pyramidal neurons
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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