| Gene Symbol | ATXN5 |
| Full Name | Ataxin-5 |
| Chromosome | 14q32.1 |
| Function | encodes a protein of 828 amino acids that is the pathogenic driver of Spinocerebellar Ataxia type 5 (SCA5), an autosomal dominant neurodegenerative disorder characterized by pure cerebellar ataxia. |
| Primary Expression | various brain regions: |
| Amino Acids | 828 aa |
| Ensembl ID | ENSG00000145833 |
| GeneCards | ATXN5 |
| Human Protein Atlas | ATXN5 |
| Nuclear receptor coactivator | Interacts with nuclear receptors and coactivators |
| Gene expression control | Regulates neuronal gene expression programs |
| Chromatin remodeling | May influence chromatin structure |
| Proteasome interactions | Associates with the ubiquitin-proteasome system |
| Autophagy regulation | Contributes to cellular clearance pathways |
| Protein homeostasis | Maintains neuronal protein equilibrium |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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