| 1960 | Milton Shy and Glenda Drager described a syndrome of autonomic failure with parkinsonism[@shy1960a] |
| 1969 | The term "Shy-Drager syndrome" came into common use following detailed clinical descriptions[@bannister1972] |
| 1989 | Multiple system atrophy (MSA) was proposed as an umbrella term encompassing Shy-Drager syndrome, striatonigral degeneration, and olivopontocerebellar atrophy[@graham1989] |
| 1998 | Discovery of α-synuclein in glial cytoplasmic inclusions established the proteinaceous basis of MSA[@spillantini1997] |
| 2008 | Second consensus criteria for MSA established modern diagnostic framework[@gilman2008] |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
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