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company 1,489 words KG: TFEB
Contents

AtlasX Bio

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Knowledge Graph

Related Hypotheses (10)

APOE-Dependent Autophagy Restoration
Score: 0.85The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69

Related Analyses (13)

Mechanistic role of APOE in neurodegeneration
neurodegeneration · archivedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archivedWhat are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completedSleep disruption as cause and consequence of neurodegenerati
neurodegeneration · completed

Related Experiments (6)

Transcriptome sequencing of cardiac fibroblasts in TFEB over
exploratory · proposed · Score: 0.90Trehalose-induced lysosomal changes and TFEB activation
exploratory · proposed · Score: 0.90Trehalose-induced lysosomal membrane permeabilization and TF
exploratory · proposed · Score: 0.90TFEB silencing and misfolded protein degradation
exploratory · proposed · Score: 0.88Functional validation of trehalose effects on misfolded prot
exploratory · proposed · Score: 0.85

Knowledge Graph (12 edges)

IL6 inhibits TFEB
TFEB regulates RRAGD
trehalose activates TFEB
TFEB regulates PPARGC1A
GABA associated_with TFEB
TFEB regulates autophagy
hederagenin activates TFEB
PPARA regulates TFEB
TFEB regulates lysosomal biogenesis
TFEB activates Autophagy-lysosomal pathway

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