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clinical 812 words KG: ent-clin-d3de9e6e
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DBS-fMRI Cognitive Decline Study (NCT06960096): Neural Basis for Cognitive Decline Following STN-DBS

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Related Hypotheses (28)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79Competitive APOE4 Domain Stabilization Peptides
Score: 0.78Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.77Multi-Modal Stress Response Harmonization
Score: 0.76Epigenetic Memory Erasure via TET2 Activation
Score: 0.74Aquaporin-4 Polarization Rescue
Score: 0.73TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73Stress Granule Phase Separation Modulators
Score: 0.72Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72Purinergic Signaling Polarization Control
Score: 0.71HDAC3-Selective Inhibition for Clock Reset
Score: 0.71Orexin-Microglia Modulation Therapy
Score: 0.71Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.71Microglial Purinergic Reprogramming
Score: 0.70Lysosomal Calcium Channel Modulation Therapy
Score: 0.70Cross-Seeding Prevention Strategy
Score: 0.69Hypocretin-Neurogenesis Coupling Therapy
Score: 0.69Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68Astrocyte MCT1/MCT4 Ratio Disruption with Metabolic Uncoupli
Score: 0.67
pg 1/2Next →

Related Analyses (20)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archivedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · completedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived

Related Experiments (4)

Brainstem Circuit Modulation for PSP
clinical · proposed · Score: 0.40Levodopa-Induced Dyskinesias Mechanism — Experiment Design
validation · proposed · Score: 0.40Cytochrome Therapeutics
clinical · proposed · Score: 0.40Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

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