cell 940 words KG: ent-gene-f71a9e3c
Contents

Hypothalamic POMC Neurons in Prader-Willi Syndrome

🔬 Protein Info
Gene Symbolent-gene-f71a9e3c
Arcuate nucleus (Arc)The medial basal hypothalamus
Pituitary pars intermediaIntermediate lobe (in some species)
Nucleus tractus solitariusBrainstem POMC population
Corticotroph lineageAnterior pituitary
MC3RExpressed in hypothalamus, regulates energy homeostasis
MC4RExpressed widely, controls appetite and metabolism
Glucose sensingRespond to changes in extracellular glucose
Leptin sensitivityExpress leptin receptors
Insulin responsivenessModulate food intake
Amino acid sensingDetect arginine, leucine
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (6)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53
...
Score: 0.68

Related Analyses (11)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

Knowledge Graph (2 edges)

ent-gene-f71a9e3c data_in benchmark_ot_ad_answer_key:POMC
benchmark_ot_ad_answer_key:POMC data_in ent-gene-f71a9e3c

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