| Gene Symbol | ent-gene-6e1f0bee |
| Chromosome | 5p13.1 |
| Heat stability | GDNF maintains activity after boiling |
| Heparin binding | Affinity for heparin sulfate proteoglycans |
| High potency | picomolar concentrations are sufficient for biological activity |
| PI3K/Akt pathway | Promotes neuron survival |
| Ras/ERK pathway | Supports neurite outgrowth |
| PLC-γ pathway | Modulates cellular responses |
| GFRα2 | Primarily binds neurturin but can also bind GDNF |
| GFRα3 | Binds artemin |
| GFRα4 | Binds persephin |
| NCAM | Can mediate GDNF signaling in some contexts |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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