cell 1,496 words KG: ent-gene-8cd44c77
Contents

Cortical NPY Neurons

🔬 Protein Info
Gene Symbolent-gene-8cd44c77
Morphologysuperior cervical ganglion NPY neuron (source: Cell Ontology)
NPYThe defining neuropeptide, visible via immunohistochemistry
Somatostatin (SST)Co-expressed in approximately 70% of cortical NPY neurons
NPY1RPrimary receptor for NPY signaling in cortical circuits
NPY2ROften expressed presynaptically to modulate neurotransmitter release
Parvalbumin (PV)Generally mutually exclusive with NPY expression
ReelinExpressed in a subset of NPY/SST co-expressing neurons
AdaptationRegular-spiking neurons with pronounced spike frequency adaptation
Low-threshold spikingSome subpopulations exhibit low-threshold calcium spikes
Haptic responsesMany respond to depolarizing inputs with delayed spiking
High input resistanceContributing to their sensitivity to small synaptic inputs
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (7)

Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.90
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53
...
Score: 0.68
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68

Related Analyses (13)

Selective vulnerability of entorhinal cortex layer II neuron
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Blood-brain barrier transport mechanisms for antibody therap
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Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

Knowledge Graph (2 edges)

ent-gene-8cd44c77 data_in benchmark_ot_ad_answer_key:NPY
benchmark_ot_ad_answer_key:NPY data_in ent-gene-8cd44c77

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