cell 1,487 words KG: ent-dise-93f3d65f
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Motor Neurons in C9orf72-Linked ALS/FTD

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Cell Typeent-dise-93f3d65f

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Related Hypotheses (9)

Smartphone-Detected Motor Variability Correction
Score: 0.74
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Cross-Seeding Prevention Strategy
Score: 0.69
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Cryptic Exon Silencing Restoration
Score: 0.53
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (12)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived

Related Experiments (25)

Progranulin Replacement Therapy for FTD — Vector Development
clinical · proposed · Score: 0.40
Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT
validation · proposed · Score: 0.40
C9orf72 Phenotype Divergence: ALS vs FTD Mechanism Study
clinical · proposed · Score: 0.40
Autophagy Enhancement Drug Screening for Neurodegeneration
clinical · proposed · Score: 0.40
Frontal and Temporal Lobe Selective Vulnerability in FTD — M
validation · proposed · Score: 0.40

Knowledge Graph (12 edges)

33300249 increased in ent-dise-93f3d65f
30458231 could be beneficial in ent-dise-93f3d65f
39317854 increase risk of ent-dise-93f3d65f
39317854 associated with increased risk of ent-dise-93f3d65f
35767949 are selectively vulnerable in ent-dise-93f3d65f
34663413 is altered in ent-dise-93f3d65f
41752118 is increasingly seen as ent-dise-93f3d65f
34873335 causes ent-dise-93f3d65f
24369373 has an oligogenic basis with ent-dise-93f3d65f
24369373 are broadening the phenotype associated with ent-dise-93f3d65f

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