| Gene Symbol | CACNB2 |
| Chromosome | 10p12.31 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | various tissues including heart, brain, and endocrine cells, and is associated with multiple neurological and cardiovascular disorders[@j2019] |
| Subcellular Localization | and regulatory properties |
| Molecular Weight | 56.7 kDa |
| Exons | 13 |
| Ensembl ID | ENSG00000165995 |
| GeneCards | CACNB2 |
| Human Protein Atlas | CACNB2 |
| SH3 domain (SRC homology 3) | Located at the N-terminus, involved in protein-protein interactions |
| Kinase domain (PKA target) | Contains serine/threonine residues phosphorylated by protein kinase A |
| C-terminal tail | Contains additional regulatory sites for phosphorylation and protein interactions |
| Activation | β2 subunits typically accelerate activation |
| Inactivation | They modulate both voltage-dependent and calcium-dependent inactivation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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