| Gene Symbol | SKIN |
| Principle | Patient-derived tau seeds template conversion of normal tau in a cyclic process |
| Detection | Immunoblotting or ELISA for amplified tau aggregates |
| Sensitivity | Comparable to RT-QuIC for detecting low-level seeding |
| Advantages | Can detect a broader range of tau conformations |
| CBS Detection | Sensitivity of 75-85% for distinguishing CBS from AD mimics |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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