biomarker 682 words KG: ent-gene-8c4b5215
Contents

gfap-biomarker-ad

🔬 Protein Info
Gene Symbolent-gene-8c4b5215
AstrocytesThe primary cellular source of GFAP, essential for brain homeostasis and immune response
Amyloid-beta (Aβ)Primary trigger of astrocytic activation in AD pathology
Phosphorylated tau biomarkersComplementary AD biomarkers used alongside GFAP assessment
NeuroinflammationThe underlying pathological
KG Connections11 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

Wikipedia

Related Hypotheses (1)

GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75

Related Analyses (3)

Neuroinflammation and microglial priming in early Alzheimer'
neurodegeneration · archived
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived

Related Experiments (30)

iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · completed · Score: 0.90
GWAS of plasma GFAP in East Asian cohort
exploratory · proposed · Score: 0.95
Plasma ATN biomarkers across AD continuum in Chilean cohort
clinical · proposed · Score: 0.95
Real-world safety study of Lecanemab in Japanese AD patients
clinical · proposed · Score: 0.95
GWAS of composite biomarker score
exploratory · proposed · Score: 0.90

Knowledge Graph (11 edges)

41918508 is a marker for ent-gene-8c4b5215
39748415 mediates ent-gene-8c4b5215
biomarkers-gfap-alzheimers describes ent-gene-8c4b5215
biomarkers-gfap-biomarker-ad describes ent-gene-8c4b5215
ent-gene-8c4b5215 data_in benchmark_ot_ad_answer_key:GFAP
benchmark_ot_ad_answer_key:GFAP data_in ent-gene-8c4b5215
39249107 correlated with ent-gene-8c4b5215
39249107 had marginal effect on ent-gene-8c4b5215
39720677 identified patients for ent-gene-8c4b5215
22749439 reduces expression of ent-gene-8c4b5215

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