| Gene Symbol | BCLXLPROTEIN |
| Full Name | Bcl-XL (BCL2 Like 1, Isoform 1) |
| Protein Family | BCL-2 family (BH1-BH4) |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | many tissues including brain, heart, and kidney |
| Molecular Weight | 26 kDa |
| UniProt ID | Q07817 |
| GeneCards | BCLXLPROTEIN |
| Human Protein Atlas | BCLXLPROTEIN |
| BH4 domain | N-terminal amphipathic helix, important for anti-apoptotic function |
| BH3 domain | Hydrophobic groove for binding pro-apoptotic proteins |
| BH1 and BH2 domains | Form the hydrophobic pocket that binds BH3 domains |
| Synaptic protection | Prevents synaptic loss in models of neurodegeneration |
| Metabolic support | Interacts with mitochondrial proteins to maintain ATP production |
| Calcium homeostasis | Modulates ER calcium release |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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