| Gene Symbol | AMPARECEPTOR |
| Function | AMPA receptors are essential for synaptic plasticity, including long-term potentiation (LTP) and long-term depression (LTD), the cellular correlates of learning and memory. |
| Subcellular Localization | </strong></td><td>Postsynaptic density, dendritic spines</td></tr> |
| GeneCards | AMPARECEPTOR |
| Human Protein Atlas | AMPARECEPTOR |
| N-terminal domain | Subunit assembly, receptor tetramerization |
| Ligand-binding domain (LBD) | Binds glutamate, flip/flop variants |
| Transmembrane domain | Four segments (M1-M4), pore formation |
| C-terminal domain (CTD) | Variable, determines interactions |
| LTP | Activity-dependent strengthening, requires GluR1 insertion |
| LTD | Activity-dependent weakening, requires GluR2 endocytosis |
| Homeostatic plasticity | Global scaling of synaptic strength |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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