| Early Stage | Episodic memory impairment, word-finding difficulties, disorientation to time |
| Moderate Stage | Progressive aphasia, apraxia, agnosia, behavioral changes |
| Severe Stage | Complete dependence, loss of verbal abilities, motor decline |
| Motor Symptoms | Resting tremor, bradykinesia, rigidity, postural instability |
| Non-Motor Symptoms | Hyposmia, sleep disorders, depression, constipation |
| Cognitive Decline | May develop into Parkinson's Disease Dementia (PDD) in up to 80% of long-term patients[@aarsland2021] |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
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