gene 1,521 words KG: NOVA1
Contents

NOVA1 — NOVA Alternative Splicing Regulator 1

🧬 Gene Info
Gene SymbolNOVA1
Full NameNOVA Alternative Splicing Regulator 1
Chromosome14q12
Functionencodes a neuron-specific RNA-binding protein on chromosome 14q12 that is a master regulator of alternative splicing in the nervous system.
Primary ExpressionNeurons (hindbrain, ventral spinal cord, hippocampus, cortex)
Amino Acids512 aa
Exons8
UniProt IDP51513
NCBI Gene ID4857
Ensembl IDENSG00000139910
OMIM602157
GeneCardsNOVA1
Human Protein AtlasNOVA1
Nuclear localization signalDirects NOVA1 to the nucleus for co-transcriptional splicing regulation
Dimerization domainNOVA1 can form homodimers and heterodimers with NOVA2
Associated DiseasesAlzheimer's Disease, Parkinson's Disease, Paraneoplastic Opsoclonus-Myoclonus Ataxia (POMA)
DatabasesGeneCardsHPASTRING

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