| Gene Symbol | 4RTAU |
| Full Name | 4R-Tau |
| Protein Type | Protein |
| Function | is a hallmark of several neurodegenerative diseases collectively called 4R-tauopathies[@buee2000]. |
| Primary Expression | a 1:1 ratio |
| Molecular Weight | ~45-65 kDa (depending on isoform) |
| Amino Acids | 441 aa |
| UniProt ID | P10636 (isoform 2) |
| Protein Name | 4R-Tau - Tau Protein with Four Repeat Domains |
| Gene | MAPT |
| Protein Class | Microtubule-associated protein |
| Isoform Length | 383-441 amino acids (4R isoforms) |
| N-terminal projection domain | Projects away from microtubules, interacts with neuronal membranes |
| Proline-rich region | Contains multiple phosphorylation sites (20+ ser/thr sites) |
| 1N, 2N isoforms | Include N-terminal inserts from exon 2/3 |
| Associated Diseases | neurodegeneration |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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