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🎯 Drug Targets

Browse 5 drug targets with druggability analysis, composite scores, and clinical context

5
Targets
0
High Druggability
0.52
Avg Score
15
Target Classes
Druggability Distribution
High: 0Medium: 5Low: 0Unknown: 0
Avg druggability score: 0.503
Clinical Pipeline
Approved: 3Phase III: 2Phase II: 0Phase I: 0Preclinical: 0
Total compounds: 9 · Approved: 3
Class All Classes Enzyme (35) Signaling Protein (25) Structural Protein (17) Protein (16) Gpcr (13) Ion Channel (12) Receptor (11) Transcription Factor (11) Ligand (10) Epigenetic Regulator (8) Transporter (8) Kinase (7) Other (4) Protease (4) Chaperone (4)
Druggability All Druggability Low (97) Medium (56) Undruggable (19) High (10) other (3)
Sort Score Druggability Gene A-Z Market Price
Filtered by: class=transporter, druggability=Medium — 5 results
SLC7A11 Cystine/glutamate transporter Approved
Transporter Medium Druggability
Score
0.62
Drug.
0.55
Safety
0.50
Drugs
2
Hyps
2
Papers
22
Small molecule inhibition of cystine/glutamate exchange
FCGRT Fc fragment of IgG receptor and transporter Approved
Transporter Medium Druggability
Score
0.60
Drug.
0.51
Safety
0.70
Drugs
1
Hyps
1
Papers
17
Monoclonal antibody blocking FcRn-mediated IgG recycling
ABCA1 ATP-binding cassette transporter A1 Approved
Transporter Medium Druggability
Score
0.56
Drug.
0.47
Safety
0.50
Drugs
1
Hyps
6
Papers
0
Small molecule modulators to enhance cholesterol efflux and HDL formation
ABCB1 P-glycoprotein Phase III
Transporter Medium Druggability
Score
0.52
Drug.
0.47
Safety
0.30
Drugs
2
Hyps
1
Papers
17
Small molecule inhibitors to reduce efflux pump activity and enhance CNS drug penetration
SLC17A7 Vesicular glutamate transporter 1 (VGLUT1) Phase III
Transporter Medium Druggability
Score
0.33
Drug.
0.53
Safety
0.60
Drugs
3
Hyps
1
Papers
3
Expression restoration — upregulating SLC17A7 transcription or stabilizing VGLUT1 protein to preserve excitatory synaptic function
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