🎯 Drug Targets

Browse 2 drug targets with druggability analysis, composite scores, and clinical context

2

Targets

2

High Druggability

0.67

Avg Score

15

Target Classes

Druggability Distribution

High: 2Medium: 0Low: 0Unknown: 0

Avg druggability score: 0.775

Clinical Pipeline

Approved: 1Phase III: 1Phase II: 0Phase I: 0Preclinical: 0

Total compounds: 3 · Approved: 1

Filtered by: class=signaling_protein, druggability=High — 2 results

BCL2L1 BCL2 Like 1 Approved

Signaling Protein High Druggability

Small molecule inhibitor of anti-apoptotic protein function

RAB7A Ras-related protein Rab-7a Phase III

Signaling Protein High Druggability

RAB7A inhibitors or modulators would block or enhance GTPase-mediated late endosome and lysosome trafficking, disrupting autophagy flux and lysosomal degradation pathways. This can either impair pathogenic protein clearance (in certain cancers) or restore lysosomal function (in storage disorders and neurodegeneration).