[Exchange] Full enrichment batch 4 — pathway diagrams, clinical trials, gene expression for 5 more hypotheses

[Exchange] Full enrichment batch 4 — pathway diagrams, clinical trials, gene expression for 5 more hypotheses

ID: 88e25c11-8f6 Priority: 88 Type: one_shot Status: open

Goal

Full enrichment for: NAD+ Depletion Rescue (h-cb833ed8), P2Y12 Inverse Agonist (h-f99ce4ca), C1q Mimetic Decoy (h-1fe4ba9b), Lysyl Oxidase Inhibition (h-82922df8), PARP1 Inhibition (h-69919c49). Each gets pathway diagram, clinical trials, gene expression context.

Acceptance Criteria

Work Log

2026-04-20 23:30 UTC — Verification pass

• Ran DB query against PostgreSQL hypotheses table for all 5 target IDs
• Confirmed all 5 hypotheses already have all 3 enrichment types populated:

- h-cb833ed8 (NAD+ Depletion Rescue / CD38/NAMPT): pathway=2051chars, trials=3500chars, gex=1534chars ✓
- h-f99ce4ca (P2Y12 Inverse Agonist / P2RY12): pathway=1045chars, trials=7427chars, gex=1746chars ✓
- h-1fe4ba9b (C1q Mimetic Decoy / C1QA): pathway=2069chars, trials=7330chars, gex=746chars ✓
- h-82922df8 (Lysyl Oxidase Inhibition / LOX/LOXL1-4): pathway=1373chars, trials=1192chars, gex=824chars ✓
- h-69919c49 (PARP1 Inhibition / PARP1): pathway=842chars, trials=3845chars, gex=676chars ✓

• All enrichment types are substantive (>200 chars pathway, >100 chars trials, >100 chars gene expression)
• Evidence: Direct PostgreSQL query via scidex.core.database.get_db()
• Result: Already resolved on main — prior enrichment batch work covered these hypotheses

Already Resolved — 2026-04-20 23:30:00Z

All 5 hypotheses verified populated on main via direct DB query.
No code changes needed; task closes as pass.

Tasks using this spec (1)

[Exchange] Full enrichment batch 4 — pathway diagrams, clini

File: 88e25c11_8f6_spec.md

Modified: 2026-04-25 23:40

Size: 1.7 KB