[Exchange] Enrich 5 thin hypotheses with deep descriptions, evidence, and pathway diagrams
ID: 3f19681e-0f2
Priority: 88
Type: one_shot
Status: open
Goal
Enrich h-470ff83e, h-a20e0cbb, h-d2722680, h-44195347, h-4113b0e8 with 2000+ word descriptions, PubMed evidence, and mermaid pathway diagrams. These have <300 char descriptions currently.
Acceptance Criteria
☐ Concrete deliverables created
☐ Work log updated with timestamped entry
Work Log
2026-04-20 17:45 UTC — Slot minimax:62
- Task reopened: previous enrichment attempt had generic wrong pathway diagrams (alpha-synuclein for non-synuclein hypotheses)
- Verified all 5 hypotheses on origin/main have existing descriptions (14-25K chars) but missing PubMed PMIDs and correct diagrams
- Ran PubMed API searches for each hypothesis topic to gather real PMIDs
- Wrote enrichment script with corrected, hypothesis-specific pathway diagrams and PubMed evidence sections
- Executed enrich_hypotheses.py — all 5 updated:
- h-470ff83e (GPR32): 13813→16917 chars, 6 PMIDs, correct DHA→RvD1→GPR32 pathway
- h-a20e0cbb (APOE4 base editing): 24727→27031 chars, 3 PMIDs, correct APOE4→base editing pathway
- h-d2722680 (TET2): 14158→16363 chars, 2 PMIDs, correct TET2 epigenetic pathway
- h-44195347 (APOE4 chaperone): 15657→17753 chars, 3 PMIDs, correct chaperone rescue pathway
- h-4113b0e8 (Noradrenergic-Tau): 13624→17313 chars, 6 PMIDs, correct DOPEGAL→AEP→tau pathway
- All hypotheses now have: real PubMed PMIDs, scientifically accurate mermaid diagrams, PubMed Evidence sections
Acceptance Criteria
☑ Concrete deliverables created
☑ Work log updated with timestamped entry