TFE3-Rearranged and TFEB-Altered Renal Cell Carcinomas: Molecular Landscape and Therapeutic Advances.

Portu M, Balsa M, Cotaina M, Anguera G, García Del Muro X et al.

Cancers (Basel) 2026

TFE3-Rearranged and TFEB-Altered Renal Cell Carcinomas: Molecular Landscape and Therapeutic Advances. Portu M(1), Balsa M(2), Cotaina M(1), Anguera G(1), García Del Muro X(2), Algaba F(3), Maroto P(1).

3 Figures Extracted

Integrated mechanistic model of MiT-RCC driven by TFE3 and TFEB alterations. In TFE3 -rearranged RCC, most fusions join a 5′ partner gene to the ...

Multistep and multiscale model of MiT family-driven renal cell carcinoma. Schematic overview linking initiating genetic events ( TFE3 gene fusions or...

Suggested diagnostic workflow for suspected MiT family renal cell carcinoma (MiT-RCC). The algorithm integrates clinical-pathologic suspicion, confirm...