Aberrant mRNA splicing and impaired hippocampal neurogenesis in Grin2b mutant mice.

Farsi Z, Nicolella A, Simmons SK, Shin W, Kang M et al.
iScience 2026
Open on PubMed

NMDA receptor dysfunction is implicated in the pathophysiology of autism spectrum disorder (ASD). Here, we investigated heterozygous mouse mutants carrying the ASD-linked C456Y mutation of