Amyotrophic Lateral Sclerosis Overview.

The purpose of this overview is to: 1.. Describe the clinical characteristics of amyotrophic lateral sclerosis (ALS); 2.. Review genetic causes of ALS; 3.. Provide an evaluation strategy to identify the genetic cause of ALS in a proband (when possible); 4.. Provide a high-level view of management of ALS; 5.. Inform genetic counseling of family members of an individual with ALS.