Does TRPML1 enhancement cause therapeutic benefit or paradoxical lysosomal dysfunction in vivo? — Analysis Notebook

CI-generated notebook stub for analysis SDA-2026-04-16-gap-debate-20260410-113045-27c7b314. The debate revealed conflicting evidence about whether TRPML1 activation rescues or worsens lysosomal function, with studies showing both therapeutic effects and calcium depletion