HERPUD1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolHERPUD1
Namehomocysteine inducible ER protein with ubiquitin like domain 1
Typeprotein-coding
Sourcemygene

Summary

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced

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