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Top 1 hypotheses ranked by tournament Elo, market confidence, debate depth, and citation provenance

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1878

Total Hypotheses

0.561

Avg Score

0.964

Top Score

841

Debates Run

All Therapeutic Mechanistic Diagnostic Methodological

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#	Hypothesis	Elo	Market	Debates	Citations	Updated	Score
🥇	A tau PTM barcode gates trans-synaptic templating diagnostic • MAPT • neurodegeneration	unrated	0.829 Market hub	1 Transcript	7	2026-04-26	0.738

Scores are composite across novelty, feasibility, impact, mechanistic plausibility, druggability, safety, and reproducibility dimensions. • View Exchange • Browse All Hypotheses