Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about scaper: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SCAPER |
| Full Name | S-Phase Cyclin-Associated Protein Homolog |
| Chromosome | 15q24.2. |
| Function | is a protein coding gene located on chromosome 15q24. |
| Primary Expression | dopaminergic neurons of the substantia nigra pars compacta, the neuronal population most vulne |
| Amino Acids | 328 aa |
| UniProt ID | [Q9BYX4](https://www.uniprot.org/uniprot/Q9BYX4) |
| NCBI Gene ID | 55856 |
| Ensembl ID | ENSG00000141741 |
| OMIM | 611493 |
| GeneCards | SCAPER |
| Human Protein Atlas | SCAPER |
| CDK Partner | SCAPER interacts with cyclin-dependent kinases (particularly CDK2) and modulates their activity during DNA synthesis |
| S-Phase Checkpoint | SCAPER helps coordinate DNA replication with cell cycle progression, preventing replication stress |
| G1/S Transition | Emerging evidence suggests SCAPER participates in the G1 to S-phase transition checkpoint |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
A["Regulatory elements"] --> B["scaper gene"]
B --> C["mRNA transcript"]
C --> D["Protein product"]
D --> E["Cellular function"]
E --> F["Disease relevance"]
B --> G["Variant effects"]
G --> F
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
class B gene
class D protein| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:SCAPER | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:SCAPER | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning scaper in their description or question text
No additional research found