Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about pericyte injury: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| PPIA-MMP9 axis | causes | pathway | 0.90 |
| APOE epsilon4 | causes | gene | 0.70 |
| APOE4 | causes | gene | 0.70 |
| Aβ | causes | protein | 0.70 |
| APOE epsilon4 | causes | gene | 0.70 |
| APOE_EPSILON4 | causes | pathway | 0.70 |
| sPDGFRB | biomarker_for | biomarker | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| APOE4-driven pericyte injury/senescence is an upstream drive | 0.720 | neurodegeneration | Does pericyte senescence drive BBB break |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-25 | 6 hypotheses Top: 0.720
neurodegeneration | 2026-04-16 | 1 hypotheses Top: 0.618
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.68 · 2026-04-25
closed · Rounds: 4 · Score: 0.70 · 2026-04-21
closed · Rounds: 4 · Score: 0.70 · 2026-04-16
Hypotheses and analyses mentioning pericyte injury in their description or question text
No additional research found