parkinsons-disease

Understanding Entity Pages

This page aggregates everything SciDEX knows about parkinsons-disease: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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flowchart TD
    N0["PARKINSONS_DISEASE"]
    N1["ALPHA_SYNUCLEIN"]
    N1 -->|"associated with"| N0
    N2["DOPAMINE_NEURONS"]
    N0 -->|"causes"| N2
    N3["SNCA"]
    N3 -->|"causes"| N0
    N4["A53T"]
    N4 -->|"causes"| N0
    N5["NEURODEGENERATION"]
    N5 -->|"contributes to"| N0
    N6["ASO"]
    N6 -->|"treats"| N0
    N7["PLK2_PROTEIN"]
    N7 -->|"associated with"| N0
    N8["C3"]
    N8 -->|"contributes to"| N0
    N9["LRRK2"]
    N9 -->|"associated with"| N0
    N10["PRKN"]
    N10 -->|"associated with"| N0
    N11["PINK1"]
    N11 -->|"associated with"| N0
    N12["PARK7"]
    N12 -->|"associated with"| N0
    N13["MULTIPLE_SCLEROSIS"]
    N0 -->|"associated with"| N13
    N14["ALZHEIMERS_DISEASE"]
    N14 -->|"associated with"| N0
    N15["MITOPHAGY"]
    N15 -->|"associated with"| N0

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 protein
    class N3 gene
    class N4 protein
    class N7 protein
    class N8 protein
    class N9 gene
    class N10 gene
    class N11 gene
    class N12 gene
    class N13 disease
    class N14 disease
    class N15 pathway

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