Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about mitochondrial-lysosomal coupling: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| LAMTOR complex function | causes (promotes contact sites that enable energy-dependen) | protein | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Mitochondrial-Lysosomal Coupling Enhancer | 0.585 | neurodegeneration | Does TFEB dysfunction cause neurodegener |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-03 | 7 hypotheses Top: 0.697
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| ZDHHC9 palmitoylates LAMTOR1 to promote renal cell carcinoma malignant progressi [PMID:41856969] | Liu B, Hou T, Liu X, Liu L, Ma Z et al. | Cell Death Dis | 2026 | 0 |
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning mitochondrial-lysosomal coupling in their description or question text
No additional research found