Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about lncRNA-9969: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
Scientific analyses that reference this entity
molecular neurobiology | 2026-04-25 | 9 hypotheses Top: 0.670
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| Autophagy receptor identification for stress granule elimination | exploratory | neurodegenerative diseases | 0.900 | 0.00 | cultured cells under arsenite | proposed | N/A |
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Roles of NAD+ in Health and Aging. [PMID:37848251] | Lautrup S, Hou Y, Fang EF, Bohr VA | Cold Spring Harbor perspective | 2024 | 0 |
| The different autophagy degradation pathways and neurodegeneration. [PMID:35134347] | Fleming A, Bourdenx M, Fujimaki M, Karab | Neuron | 2022 | 0 |
| WDR45 contributes to neurodegeneration through regulation of ER homeostasis and [PMID:31204559] | ["Wan Huida", "Wang Qi", "Chen Xiuting", | Autophagy | 2020 | 0 |
| WDR45 contributes to neurodegeneration through regulation of ER homeostasis and [PMID:31204559] | ["Wan Huida", "Wang Qi", "Chen Xiuting", | Autophagy | 2020 | 0 |
| Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive defi [PMID:30742114] | Unknown | Nature neuroscience | 2019 | 0 |
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning lncRNA-9969 in their description or question text
Score: 0.421 · molecular neurobiology · 2026-04-20
## Mechanistic Overview Alpha-Theta Oscillation Modulation Enhances lncRNA-9969-Mediated Autophagy Through SST Interneur
Score: 0.380 · molecular neurobiology · 2026-04-26
This hypothesis proposes that lncRNA-9969's selective sequestration of miR-6361 in parvalbumin interneurons operates thr
Score: 0.380 · molecular neurobiology · 2026-04-27
This hypothesis proposes that lncRNA-9969, when upregulated by CREB1 activation in parvalbumin (PV) interneurons, employ
Score: 0.380 · molecular neurobiology · 2026-04-27
**Molecular Mechanism and Rationale** This therapeutic mechanism centers on a distinct circuit-RNA regulatory network th
Score: 0.380 · molecular neurobiology · 2026-04-26
This hypothesis proposes that theta-gamma cross-frequency coupling (TGC) regulates lncRNA-9969 function through phase-de