Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about histone modifications: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Therapy Resistance | contributes_to | phenotype | 0.90 |
| Primary Open Angle Glaucoma | involved_in | disease | 0.90 |
| Neuroinflammation | regulates | process | 0.85 |
| Tumor Evolution | associated_with | process | 0.85 |
| Alzheimer's disease | associated_with | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Gut Microbiota | modulates | process | 0.95 |
| Gut Microbiota Metabolites | modulates | compound | 0.85 |
| ketone bodies | regulates | metabolite | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
metabolic neuroscience | 2026-04-03 | 7 hypotheses Top: 0.773
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning histone modifications in their description or question text
No additional research found