Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about autism-spectrum-disorder: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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flowchart TD
N0["autism spectrum disorder"]
N1["pyroptosis"]
N0 -->|"involves"| N1
N2["oxidative stress response"]
N0 -->|"involves"| N2
N3["apoptosis pathway"]
N0 -->|"involves"| N3
N4["ROS"]
N4 -->|"activates"| N0
N5["NLRP3"]
N5 -->|"activates"| N0
N6["GSDMD"]
N6 -->|"activates"| N0
N7["RhoA"]
N7 -->|"associated with"| N0
N8["necroptosis"]
N0 -->|"involves"| N8
N9["ubiquitin-proteasome"]
N0 -->|"involves"| N9
N10["MAPK signaling"]
N0 -->|"involves"| N10
N11["ferroptosis"]
N0 -->|"involves"| N11
N12["NF-kB signaling"]
N0 -->|"involves"| N12
N13["mitochondrial function"]
N0 -->|"involves"| N13
N14["NLGN1"]
N14 -->|"associated with"| N0
N15["PVALB"]
N15 -->|"associated with"| N0
N16["CYP19A1"]
N16 -->|"associated with"| N0
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
class N1 pathway
class N2 pathway
class N3 pathway
class N4 gene
class N5 gene
class N6 gene
class N7 protein
class N8 pathway
class N9 pathway
class N10 pathway
class N11 pathway
class N12 pathway
class N13 pathway
class N14 protein
class N15 protein
class N16 gene| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning autism-spectrum-disorder in their description or question text
No additional research found