CD274

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCD274
NameCD274 molecule
Typeprotein-coding
Sourcemygene

Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maint

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This is an externally resolved entity

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